{"id":24646,"date":"2023-11-16T10:15:31","date_gmt":"2023-11-16T10:15:31","guid":{"rendered":"https:\/\/www.alttechindustries.com\/?p=24646"},"modified":"2023-11-16T10:37:40","modified_gmt":"2023-11-16T10:37:40","slug":"20-year-study-shows-alarming-antibiotic-resistance-in-perio-patient","status":"publish","type":"post","link":"https:\/\/www.alttechindustries.com\/20-year-study-shows-alarming-antibiotic-resistance-in-perio-patient\/","title":{"rendered":"20-year study shows “alarming” antibiotic resistance in perio patient!"},"content":{"rendered":"\t\t
\n\t\t\t\t\t\t\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
What is the implications for Dentistry?<\/h2>
All this confusion and concern over antibiotic resistance and dentistry.<\/p>
As Porphyromonas gingivalis, the main pathogen of gingivitis as well as other periodontist-assorted bacteria has shown an increase in resistance to antibiotics.<\/p>
Using biofilm samples from three sets of patients with severe periodontitis from three time frames\u20141999\u20132000, 2009\u20132010, and 2019\u20132020\u2014researchers from the Temple University School of Dentistry and the University Medical Center Groningen in the Netherlands determined that in the earliest set of patients, resistance to clindamycin affected .6% of patients, but by the last set, that percentage rose to 9.3%.\u00a0P. gingivalis<\/em>\u00a0resistance to amoxicillin increased from 0.1% of patients in 1999\u20132000 to 2.8% in 2019\u20132020, a 28-fold increase<\/p>
The study authors say the findings are the first to show substantial increases over 20 years in clindamycin-resistant and amoxicillin-resistant\u00a0P. gingivalis<\/em>\u00a0in US periodontitis patients, calling the current rate of US clindamycin resistance \u201calarming.\u201d<\/p>
\u201cClindamycin was shown over 3 decades ago to be useful in resolving\u00a0P. gingivalis<\/em>-associated refractory cases of periodontitis and arresting progressive periodontal attachment loss\u2026 Clindamycin is additionally recommended by the American Academy of Periodontology as an empirical antibiotic choice in the treatment of periodontal abscesses, where\u00a0P. gingivalis<\/em>\u00a0is often part of the associated microbial etiology,\u201d the study states. \u201cHowever, due to the increased prevalence of clindamycin-resistant\u00a0P. gingivalis<\/em>, as documented in the present study, these recommendations likely need to be reconsidered and appropriately modified.\u201d<\/p>